The Imaging core will provide comprehensive support for the in vivo imaging studies carried out within the Program Project. The core is divided into two sections operated at the BioMedical Engineering and Imaging Institute (BMEII) at Mount Sinai and at Massachusetts General Hospital (MGH). Under the direction of the Core Director, Dr. Venkatesh Mani, the core will assist with the technical imaging protocol development and implementation and also serve as the image and data repository for data obtained from all three projects.